The Bar Lab studies novel approaches to HIV prevention and cure.
Characterizing the viral dynamics and host immune responses during virus suppression and treatment interruption.
Scanning electron micrograph of HIV-1 virions (green) budding from a cultured lymphocyte. Multiple round bumps on the cell surface represent sites of virion assembly and budding. (Ref)
Developing Non-Human Primate (NHP) models that faithfully recapitulate HIV-1 latency and rebound.
Rhesus macaque (Macaca mulatta mulatta), male, Gokarna Forest, Near Kathmandu, Nepal (Ref)
Developing antibody-based interventions
A three-dimensional X-ray crystallographic image showing a broadly neutralizing antibody (green) bound to a vaccine target (yellow) on an HIV-1 gp120 molecule (red). Ref
Globally, 37.7 million people were living with HIV at the end of 2020. An estimated 0.7% of adults aged 15–49 years worldwide are living with HIV, although the burden of the epidemic continues to vary considerably between countries and regions.
Photo Credit: Ian Cuming/Getty